Drinking in Middle Age May Accelerate Cognitive Decline

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Drinking in Middle Age May Accelerate Cognitive Decline



Middle-aged men who drink 36 grams or more of alcohol a day, or a little more than 2 and a half standard drinks, are more likely to experience faster decline in all cognitive areas ― but especially memory ― during a period of 10 years, translating into 5.7 years of extra cognitive aging, a new study suggests.


The association for women in the study is less clear, although women who drink 19 or more grams per day of alcohol may experience faster decline in executive function. Interestingly, women who abstain from drinking also have faster declines in certain cognitive domains.


"Excessive alcohol consumption is known to have detrimental short- and long-term effects on the brain, but the effect of consumption of around 3 to 4 drinks per day is less clear," said lead author Séverine Sabia, PhD, Department of Epidemiology and Public Health, University College London, United Kingdom.


Unlike much of the previous research on the impact of alcohol consumption on cognition, the current study included middle-aged persons. "The elderly may have reduced their alcohol consumption due to health concerns," said Dr. Sabia. "In many of the previous studies, the effect of heavy drinking was difficult to assess due to the small number of heavy drinkers."


The study was published online January 15 in Neurology.

http://www.medscape.com/viewarticle/819242
 
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