i hope the parties concerned, that there has been only one recorded instance of immaculate conception, and that happened around 2000 years or so ago, in bethlehem.
i wish this couple well, and may venture to suggest, that as a supplement to all the prayers, that they do indulge in coitus regularly and often many times a day, and ofcourse relaxedly and enjoyably. i have heard that the right mood is important.
again, we are assuming that all the relevant details re sperm count, female cycle fertility and what else, has been thoroughly vetted out. i think it is good to approach to take all the help that one can get from all quarters, and if successful, pay due obeisance to the same all quarters, for one really does not know where the help comes from in these matters.
finally, after a time boxed period, they may consider adoption.
best wishes for an early fulfillment.